Stop codon readthrough contexts influence reporter expression differentially depending on the presence of an IRES

Abstract Background: Previously we reported the discovery of stop codon readthrough in AMD1 mRNA followed by ribosome stalling at the end of a conserved Open Reading Frame (ORF) that we termed AMD1. To explain the severe suppression of reporters fused to AMD1 tail we proposed a mechanism invoking ri...

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Detalles Bibliográficos
Autores principales: Yordanova, Martina M., Loughran, Gary, Atkins, John F., Baranov, Pavel V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831848/
https://www.ncbi.nlm.nih.gov/pubmed/35187266
http://dx.doi.org/10.12688/wellcomeopenres.16231.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831848/
https://www.ncbi.nlm.nih.gov/pubmed/35187266
http://dx.doi.org/10.12688/wellcomeopenres.16231.3

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