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Stop codon readthrough contexts influence reporter expression differentially depending on the presence of an IRES
Abstract Background: Previously we reported the discovery of stop codon readthrough in AMD1 mRNA followed by ribosome stalling at the end of a conserved Open Reading Frame (ORF) that we termed AMD1. To explain the severe suppression of reporters fused to AMD1 tail we proposed a mechanism invoking ri...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831848/ https://www.ncbi.nlm.nih.gov/pubmed/35187266 http://dx.doi.org/10.12688/wellcomeopenres.16231.3 |