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Characterization of Chromosomal Instability in Glioblastoma

Glioblastoma multiforme (GBM) is a malignant tumor of the central nervous system (CNS). The poor prognosis of GBM due to resistance to therapy has been associated with high chromosomal instability (CIN). Replication stress is a major cause of CIN that manifests as chromosome rearrangements, fragilit...

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Detalles Bibliográficos
Autores principales: Balzano, Elisa, Di Tommaso, Elena, Antoccia, Antonio, Pelliccia, Franca, Giunta, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831864/
https://www.ncbi.nlm.nih.gov/pubmed/35154254
http://dx.doi.org/10.3389/fgene.2021.810793