GATA3 Truncation Mutants Alter EMT Related Gene Expression via Partial Motif Recognition in Luminal Breast Cancer Cells

GATA3 is known to be one of the most frequently mutated genes in breast cancer. More than 10% of breast tumors carry mutations in this gene. However, the functional consequence of GATA3 mutations is still largely unknown. Clinical data suggest that different types of GATA3 mutations may have distinc...

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Detalles Bibliográficos
Autores principales: Saotome, Mika, Poduval, Deepak Balakrishnan, Nair, Renju, Cooper, Mikhala, Takaku, Motoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831884/
https://www.ncbi.nlm.nih.gov/pubmed/35154280
http://dx.doi.org/10.3389/fgene.2022.820532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831884/
https://www.ncbi.nlm.nih.gov/pubmed/35154280
http://dx.doi.org/10.3389/fgene.2022.820532

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