Cargando…
GATA3 Truncation Mutants Alter EMT Related Gene Expression via Partial Motif Recognition in Luminal Breast Cancer Cells
GATA3 is known to be one of the most frequently mutated genes in breast cancer. More than 10% of breast tumors carry mutations in this gene. However, the functional consequence of GATA3 mutations is still largely unknown. Clinical data suggest that different types of GATA3 mutations may have distinc...
Autores principales: | Saotome, Mika, Poduval, Deepak Balakrishnan, Nair, Renju, Cooper, Mikhala, Takaku, Motoki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831884/ https://www.ncbi.nlm.nih.gov/pubmed/35154280 http://dx.doi.org/10.3389/fgene.2022.820532 |
Ejemplares similares
-
Genomic transcription factor binding site selection is edited by the chromatin remodeling factor CHD4
por: Saotome, Mika, et al.
Publicado: (2023) -
Interaction of the pioneer transcription factor GATA3 with nucleosomes
por: Tanaka, Hiroki, et al.
Publicado: (2020) -
P4HTM: A Novel Downstream Target of GATA3 in Breast Cancer
por: DiDonna, Sarah C., et al.
Publicado: (2023) -
GATA3 frameshift mutation promotes tumor growth in human luminal breast cancer cells and induces transcriptional changes seen in primary GATA3 mutant breast cancers
por: Gustin, John P., et al.
Publicado: (2017) -
Tumor Budding: The Name is EMT. Partial EMT.
por: Grigore, Alexandru Dan, et al.
Publicado: (2016)