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Berberine ameliorates aGVHD by gut microbiota remodelling, TLR4 signalling suppression and colonic barrier repairment for NLRP3 inflammasome inhibition

Berberine (BBR), an isoquinoline alkaloid, is used to treat gastrointestinal disorders as an herbal medicine in China. The aim of this study was to investigate the anti‐inflammatory activities of BBR in a mouse model with acute graft‐versus‐host disease (aGVHD). Mice were intravenously injected with...

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Detalles Bibliográficos
Autores principales: Zhao, Yanna, Huang, Jiefeng, Li, Tianyi, Zhang, Shuijuan, Wen, Chengping, Wang, Lipei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831946/
https://www.ncbi.nlm.nih.gov/pubmed/34984827
http://dx.doi.org/10.1111/jcmm.17158