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FGF21 attenuates pulmonary arterial hypertension via downregulation of miR‐130, which targets PPARγ

The proliferation, migration and apoptotic resistance of pulmonary artery smooth muscle cells (PASMCs) are central to the progression of pulmonary arterial hypertension (PAH). Our previous study identified that fibroblast growth factor 21 (FGF21) regulates signalling pathway molecules, such as perox...

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Detalles Bibliográficos
Autores principales: Wang, Meibin, Su, Lihuang, Sun, Junwei, Cai, Luqiong, Li, Xiuchun, Zhu, Xiayan, Song, Lanlan, Li, Jingyin, Tong, Shuolan, He, Qinlian, Cai, Mengsi, Yang, Lehe, Chen, Yanfan, Wang, Liangxing, Huang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831951/
https://www.ncbi.nlm.nih.gov/pubmed/34989130
http://dx.doi.org/10.1111/jcmm.17154