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Broussonin A– and B–mediated inhibition of angiogenesis by blockade of VEGFR‐2 signalling pathways and integrin β1 expression

In the present study, we demonstrate the regulatory effects and mechanism of broussonin A and B, diphenylpropane derivatives isolated from Broussonetia kazinoki, on vascular endothelial growth factor‐A (VEGF‐A)–stimulated endothelial cell responses in vitro and microvessel sprouting ex vivo. Treatme...

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Detalles Bibliográficos
Autores principales: Kim, Jae Hyeon, Kim, Sunho, Han, Surim, Ahn, Eun‐Kyung, Cho, Young‐Rak, Jeong, Wonsik, Kim, Sung Joon, Bae, Gyu‐Un, Oh, Joa Sub, Seo, Dong‐Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831976/
https://www.ncbi.nlm.nih.gov/pubmed/34994065
http://dx.doi.org/10.1111/jcmm.17173