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Vorinostat Corrects Cognitive and Non-Cognitive Symptoms in a Mouse Model of Fragile X Syndrome

BACKGROUND: Fragile X syndrome (FXS) is caused by mutations in the FMR1 gene. It is a form of heritable intellectual disability and autism. Despite recent advance in elucidating disease mechanisms, there is no efficacious medication. Because de novo drug development is a lengthy process, repurposing...

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Detalles Bibliográficos
Autores principales: Ding, Qi, Wu, Xueting, Li, Xuan, Wang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832232/
https://www.ncbi.nlm.nih.gov/pubmed/34791268
http://dx.doi.org/10.1093/ijnp/pyab081