MUC1-C dictates neuroendocrine lineage specification in pancreatic ductal adenocarcinomas

Pancreatic ductal adenocarcinomas (PDAC) and poorly differentiated pancreatic neuroendocrine (NE) carcinomas are KRAS mutant malignancies with a potential common cell of origin. PDAC ductal, but not NE, lineage traits have been associated with cell-intrinsic activation of interferon (IFN) pathways....

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Detalles Bibliográficos
Autores principales: Luan, Zhou, Morimoto, Yoshihiro, Fushimi, Atsushi, Yamashita, Nami, Suo, Wenhao, Bhattacharya, Atrayee, Hagiwara, Masayuki, Jin, Caining, Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Carcinogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832436/
https://www.ncbi.nlm.nih.gov/pubmed/34657147
http://dx.doi.org/10.1093/carcin/bgab097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832436/
https://www.ncbi.nlm.nih.gov/pubmed/34657147
http://dx.doi.org/10.1093/carcin/bgab097

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