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MUC1-C dictates neuroendocrine lineage specification in pancreatic ductal adenocarcinomas
Pancreatic ductal adenocarcinomas (PDAC) and poorly differentiated pancreatic neuroendocrine (NE) carcinomas are KRAS mutant malignancies with a potential common cell of origin. PDAC ductal, but not NE, lineage traits have been associated with cell-intrinsic activation of interferon (IFN) pathways....
Autores principales: | Luan, Zhou, Morimoto, Yoshihiro, Fushimi, Atsushi, Yamashita, Nami, Suo, Wenhao, Bhattacharya, Atrayee, Hagiwara, Masayuki, Jin, Caining, Kufe, Donald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832436/ https://www.ncbi.nlm.nih.gov/pubmed/34657147 http://dx.doi.org/10.1093/carcin/bgab097 |
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