Neutrophil HIF-1α stabilization is augmented by mitochondrial ROS produced via the glycerol 3-phosphate shuttle

Neutrophils are predominantly glycolytic cells that derive little ATP from oxidative phosphorylation; however, they possess an extensive mitochondrial network and maintain a mitochondrial membrane potential. Although studies have shown neutrophils need their mitochondria to undergo apoptosis and reg...

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Detalles Bibliográficos
Autores principales: Willson, Joseph A., Arienti, Simone, Sadiku, Pranvera, Reyes, Leila, Coelho, Patricia, Morrison, Tyler, Rinaldi, Giulia, Dockrell, David H., Whyte, Moira K. B., Walmsley, Sarah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832465/
https://www.ncbi.nlm.nih.gov/pubmed/34411229
http://dx.doi.org/10.1182/blood.2021011010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832465/
https://www.ncbi.nlm.nih.gov/pubmed/34411229
http://dx.doi.org/10.1182/blood.2021011010

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