Aged healthy mice acquire clonal hematopoiesis mutations

Chin and colleagues used detailed mutational analysis of aged mice and transplantation to evaluate the mouse as a model of clonal hematopoiesis (CH). Their data suggest that while murine hematopoietic stem cells acquire mutations in CH-associated genes when aged and CH clones can expand after transp...

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Detalles Bibliográficos
Autores principales: Chin, Desmond Wai Loon, Yoshizato, Tetsuichi, Virding Culleton, Stina, Grasso, Francesca, Barbachowska, Magdalena, Ogawa, Seishi, Jacobsen, Sten Eirik W., Woll, Petter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Letter to Blood
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832470/
https://www.ncbi.nlm.nih.gov/pubmed/34665864
http://dx.doi.org/10.1182/blood.2021014235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832470/
https://www.ncbi.nlm.nih.gov/pubmed/34665864
http://dx.doi.org/10.1182/blood.2021014235

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