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Intervertebral Disc-on-a-Chip as Advanced In Vitro Model for Mechanobiology Research and Drug Testing: A Review and Perspective

Discogenic back pain is one of the most diffused musculoskeletal pathologies and a hurdle to a good quality of life for millions of people. Existing therapeutic options are exclusively directed at reducing symptoms, not at targeting the underlying, still poorly understood, degenerative processes. Co...

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Detalles Bibliográficos
Autores principales: Mainardi, Andrea, Cambria, Elena, Occhetta, Paola, Martin, Ivan, Barbero, Andrea, Schären, Stefan, Mehrkens, Arne, Krupkova, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832503/
https://www.ncbi.nlm.nih.gov/pubmed/35155416
http://dx.doi.org/10.3389/fbioe.2021.826867