Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Protects Striatal Cells and Improves Motor Function in Huntington’s Disease Models: Role of PAC1 Receptor

Huntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the expression of mutant huntingtin (mHtt). One of the main features of HD is the degeneration of the striatum that leads to motor discoordination. Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropept...

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Detalles Bibliográficos
Autores principales: Solés-Tarrés, Irene, Cabezas-Llobet, Núria, Lefranc, Benjamin, Leprince, Jérôme, Alberch, Jordi, Vaudry, David, Xifró, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832515/
https://www.ncbi.nlm.nih.gov/pubmed/35153755
http://dx.doi.org/10.3389/fphar.2021.797541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832515/
https://www.ncbi.nlm.nih.gov/pubmed/35153755
http://dx.doi.org/10.3389/fphar.2021.797541

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