Genetic and functional evidence for gp130/IL6ST-induced transient receptor potential ankyrin 1 upregulation in uninjured but not injured neurons in a mouse model of neuropathic pain

Peripheral nerve injuries result in pronounced alterations in dorsal root ganglia, which can lead to the development of neuropathic pain. Although the polymodal mechanosensitive transient receptor potential ankyrin 1 (TRPA1) ion channel is emerging as a relevant target for potential analgesic therap...

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Detalles Bibliográficos
Autores principales: Kalpachidou, Theodora, Malsch, Philipp, Qi, Yanmei, Mair, Norbert, Geley, Stephan, Quarta, Serena, Kummer, Kai K., Kress, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832546/
https://www.ncbi.nlm.nih.gov/pubmed/34252913
http://dx.doi.org/10.1097/j.pain.0000000000002402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832546/
https://www.ncbi.nlm.nih.gov/pubmed/34252913
http://dx.doi.org/10.1097/j.pain.0000000000002402

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