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Genetic and functional evidence for gp130/IL6ST-induced transient receptor potential ankyrin 1 upregulation in uninjured but not injured neurons in a mouse model of neuropathic pain
Peripheral nerve injuries result in pronounced alterations in dorsal root ganglia, which can lead to the development of neuropathic pain. Although the polymodal mechanosensitive transient receptor potential ankyrin 1 (TRPA1) ion channel is emerging as a relevant target for potential analgesic therap...
Autores principales: | Kalpachidou, Theodora, Malsch, Philipp, Qi, Yanmei, Mair, Norbert, Geley, Stephan, Quarta, Serena, Kummer, Kai K., Kress, Michaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832546/ https://www.ncbi.nlm.nih.gov/pubmed/34252913 http://dx.doi.org/10.1097/j.pain.0000000000002402 |
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