Concomitant novel ALK-SSH2, EML4-ALK and ARID2-ALK, EML4-ALK double-fusion variants and confer sensitivity to crizotinib in two lung adenocarcinoma patients, respectively

INTRODUCTION: Anaplastic lymphoma kinase (ALK) gene rearrangements, have been identified in approximately 2-7% of patients with lung adenocarcinoma (LUAD). However, co-occurrence of double ALK fusions in one patient was rare. Herein, we reported two Chinese female LUAD patients with confirmed double...

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Detalles Bibliográficos
Autores principales: Tao, Hong, Liu, Zhe, Mu, Jing, Gai, Fei, Huang, Zhan, Shi, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832643/
https://www.ncbi.nlm.nih.gov/pubmed/35144623
http://dx.doi.org/10.1186/s13000-022-01212-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832643/
https://www.ncbi.nlm.nih.gov/pubmed/35144623
http://dx.doi.org/10.1186/s13000-022-01212-9

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