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The role of S100B/RAGE-enhanced ADAM17 activation in endothelial glycocalyx shedding after traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) remains one of the main causes for disability and death worldwide. While the primary mechanical injury cannot be avoided, the prevention of secondary injury is the focus of TBI research. Present study aimed to elucidate the effects and mechanisms of S100B and...

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Detalles Bibliográficos
Autores principales: Zou, Zhimin, Li, Li, Li, Qin, Zhao, Peng, Zhang, Kun, Liu, Chengyong, Cai, Daozhang, Maegele, Marc, Gu, Zhengtao, Huang, Qiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832692/
https://www.ncbi.nlm.nih.gov/pubmed/35148784
http://dx.doi.org/10.1186/s12974-022-02412-2