Ryanodine receptor RyR1-mediated elevation of Ca(2+) concentration is required for the late stage of myogenic differentiation and fusion

BACKGROUND: Cytosolic Ca(2+) plays vital roles in myogenesis and muscle development. As a major Ca(2+) release channel of endoplasmic reticulum (ER), ryanodine receptor 1 (RyR1) key mutations are main causes of severe congenital myopathies. The role of RyR1 in myogenic differentiation has attracted...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Kai, Wang, Yubo, Xu, Doudou, He, Linjuan, Zhang, Xin, Yan, Enfa, Wang, Lu, Yin, Jingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832842/
https://www.ncbi.nlm.nih.gov/pubmed/35144690
http://dx.doi.org/10.1186/s40104-021-00668-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832842/
https://www.ncbi.nlm.nih.gov/pubmed/35144690
http://dx.doi.org/10.1186/s40104-021-00668-x

Ejemplares similares