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RAGE mediates airway inflammation via the HDAC1 pathway in a toluene diisocyanate-induced murine asthma model

BACKGROUND: Exposure to toluene diisocyanate (TDI) is a significant pathogenic factor for asthma. We previously reported that the receptor for advanced glycation end products (RAGE) plays a key role in TDI-induced asthma. Histone deacetylase (HDAC) has been reported to be important in asthmatic path...

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Detalles Bibliográficos
Autores principales: Peng, Xianru, Huang, Minyu, Zhao, Wenqu, Lan, Zihan, Wang, Xiaohua, Yuan, Yafei, Li, Bohou, Yu, Changhui, Liu, Laiyu, Dong, Hangming, Cai, Shaoxi, Zhao, Haijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832863/
https://www.ncbi.nlm.nih.gov/pubmed/35148729
http://dx.doi.org/10.1186/s12890-022-01832-3