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Epigenetic state determines inflammatory sensing in neuroblastoma

Immunotherapy has revolutionized cancer treatment, but many cancers are not impacted by currently available immunotherapeutic strategies. Here, we investigated inflammatory signaling pathways in neuroblastoma, a classically “cold” pediatric cancer. By testing the functional response of a panel of 20...

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Detalles Bibliográficos
Autores principales: Wolpaw, Adam J., Grossmann, Liron D., Dessau, Jessica L., Dong, May M., Aaron, Bailey J., Brafford, Patricia A., Volgina, Darya, Pascual-Pasto, Guillem, Rodriguez-Garcia, Alba, Uzun, Yasin, Arsenian-Henriksson, Marie, Powell, Daniel J., Bosse, Kristopher R., Kossenkov, Andrew, Tan, Kai, Hogarty, Michael D., Maris, John M., Dang, Chi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832972/
https://www.ncbi.nlm.nih.gov/pubmed/35121657
http://dx.doi.org/10.1073/pnas.2102358119