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MRP5 and MRP9 play a concerted role in male reproduction and mitochondrial function
Multidrug Resistance Proteins (MRPs) are transporters that play critical roles in cancer even though the physiological substrates of these enigmatic transporters are poorly elucidated. In Caenorhabditis elegans, MRP5/ABCC5 is an essential heme exporter because mrp-5 mutants are unviable due to their...
Autores principales: | Chambers, Ian G., Kumar, Praveen, Lichtenberg, Jens, Wang, Pengcheng, Yu, Jianshi, Phillips, John D., Kane, Maureen A., Bodine, David, Hamza, Iqbal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832985/ https://www.ncbi.nlm.nih.gov/pubmed/35121660 http://dx.doi.org/10.1073/pnas.2111617119 |
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