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Targeting regulation of ATP synthase 5 alpha/beta dimerization alleviates senescence

Senescence is a distinct set of changes in the senescence-associated secretory phenotype (SASP) and leads to aging and age-related diseases. Here, we screened compounds that could ameliorate senescence and identified an oxazoloquinoline analog (KB1541) designed to inhibit IL-33 signaling pathway. To...

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Detalles Bibliográficos
Autores principales: Lee, Yun Haeng, Choi, Doyoung, Jang, Geonhee, Park, Ji Yun, Song, Eun Seon, Lee, Haneur, Kuk, Myeong Uk, Joo, Junghyun, Ahn, Soon Kil, Byun, Youngjoo, Park, Joon Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833107/
https://www.ncbi.nlm.nih.gov/pubmed/35093936
http://dx.doi.org/10.18632/aging.203858