Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile

Aging is associated with cognitive decline and accumulation of senescent cells in various tissues and organs. Senolytic agents such as dasatinib and quercetin (D+Q) in combination have been shown to target senescent cells and ameliorate symptoms of aging-related disorders in mouse models. However, t...

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Detalles Bibliográficos
Autores principales: Krzystyniak, Adam, Wesierska, Malgorzata, Petrazzo, Gregory, Gadecka, Agnieszka, Dudkowska, Magdalena, Bielak-Zmijewska, Anna, Mosieniak, Grazyna, Figiel, Izabela, Wlodarczyk, Jakub, Sikora, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833137/
https://www.ncbi.nlm.nih.gov/pubmed/35042834
http://dx.doi.org/10.18632/aging.203835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833137/
https://www.ncbi.nlm.nih.gov/pubmed/35042834
http://dx.doi.org/10.18632/aging.203835

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