Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy

In persons living with HIV-1 (PLWH) who start antiretroviral therapy (ART), plasma virus decays in a biphasic fashion to below the detection limit. The first phase reflects the short half-life (<1 d) of cells that produce most of the plasma virus. The second phase represents the slower turnover (...

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Detalles Bibliográficos
Autores principales: White, Jennifer A., Simonetti, Francesco R., Beg, Subul, McMyn, Natalie F., Dai, Weiwei, Bachmann, Niklas, Lai, Jun, Ford, William C., Bunch, Christina, Jones, Joyce L., Ribeiro, Ruy. M., Perelson, Alan S., Siliciano, Janet D., Siliciano, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833145/
https://www.ncbi.nlm.nih.gov/pubmed/35110411
http://dx.doi.org/10.1073/pnas.2120326119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833145/
https://www.ncbi.nlm.nih.gov/pubmed/35110411
http://dx.doi.org/10.1073/pnas.2120326119

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