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Leucine retention in lysosomes is regulated by starvation

Cells acquire essential nutrients from the environment and utilize adaptive mechanisms to survive when nutrients are scarce. How nutrients are trafficked and compartmentalized within cells and whether they are stored in response to stress remain poorly understood. Here, we investigate amino acid tra...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Urmi, Todorova, Pavlina, Pavlova, Natalya N., Tada, Yuma, Thompson, Craig B., Finley, Lydia W.S., Overholtzer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833167/
https://www.ncbi.nlm.nih.gov/pubmed/35105808
http://dx.doi.org/10.1073/pnas.2114912119