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Leucine retention in lysosomes is regulated by starvation
Cells acquire essential nutrients from the environment and utilize adaptive mechanisms to survive when nutrients are scarce. How nutrients are trafficked and compartmentalized within cells and whether they are stored in response to stress remain poorly understood. Here, we investigate amino acid tra...
Autores principales: | Bandyopadhyay, Urmi, Todorova, Pavlina, Pavlova, Natalya N., Tada, Yuma, Thompson, Craig B., Finley, Lydia W.S., Overholtzer, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833167/ https://www.ncbi.nlm.nih.gov/pubmed/35105808 http://dx.doi.org/10.1073/pnas.2114912119 |
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