Impact of ADAR-induced editing of minor viral RNA populations on replication and transmission of SARS-CoV-2

Adenosine deaminases acting on RNA (ADAR) are RNA-editing enzymes that may restrict viral infection. We have utilized deep sequencing to determine adenosine to guanine (A→G) mutations, signifying ADAR activity, in clinical samples retrieved from 93 severe acute respiratory syndrome coronavirus 2 (SA...

Descripción completa

Detalles Bibliográficos
Autores principales: Ringlander, Johan, Fingal, Joshua, Kann, Hanna, Prakash, Kasthuri, Rydell, Gustaf, Andersson, Maria, Martner, Anna, Lindh, Magnus, Horal, Peter, Hellstrand, Kristoffer, Kann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833170/
https://www.ncbi.nlm.nih.gov/pubmed/35064076
http://dx.doi.org/10.1073/pnas.2112663119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833170/
https://www.ncbi.nlm.nih.gov/pubmed/35064076
http://dx.doi.org/10.1073/pnas.2112663119

Ejemplares similares