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Impact of ADAR-induced editing of minor viral RNA populations on replication and transmission of SARS-CoV-2

Adenosine deaminases acting on RNA (ADAR) are RNA-editing enzymes that may restrict viral infection. We have utilized deep sequencing to determine adenosine to guanine (A→G) mutations, signifying ADAR activity, in clinical samples retrieved from 93 severe acute respiratory syndrome coronavirus 2 (SA...

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Detalles Bibliográficos
Autores principales:	Ringlander, Johan, Fingal, Joshua, Kann, Hanna, Prakash, Kasthuri, Rydell, Gustaf, Andersson, Maria, Martner, Anna, Lindh, Magnus, Horal, Peter, Hellstrand, Kristoffer, Kann, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833170/ https://www.ncbi.nlm.nih.gov/pubmed/35064076 http://dx.doi.org/10.1073/pnas.2112663119

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