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Domoic acid biosynthesis in the red alga Chondria armata suggests a complex evolutionary history for toxin production

Domoic acid (DA), the causative agent of amnesic shellfish poisoning, is produced by select organisms within two distantly related algal clades: planktonic diatoms and red macroalgae. The biosynthetic pathway to isodomoic acid A was recently solved in the harmful algal bloom–forming diatom Pseudonit...

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Detalles Bibliográficos
Autores principales: Steele, Taylor S., Brunson, John K., Maeno, Yukari, Terada, Ryuta, Allen, Andrew E., Yotsu-Yamashita, Mari, Chekan, Jonathan R., Moore, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833176/
https://www.ncbi.nlm.nih.gov/pubmed/35110408
http://dx.doi.org/10.1073/pnas.2117407119