High-speed atomic force microscopy reveals a three-state elevator mechanism in the citrate transporter CitS

The secondary active transporter CitS shuttles citrate across the cytoplasmic membrane of gram-negative bacteria by coupling substrate translocation to the transport of two Na(+) ions. Static crystal structures suggest an elevator type of transport mechanism with two states: up and down. However, no...

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Detalles Bibliográficos
Autores principales: Maity, Sourav, Trinco, Gianluca, Buzón, Pedro, Anshari, Zaid R., Kodera, Noriyuki, Ngo, Kien Xuan, Ando, Toshio, Slotboom, Dirk J., Roos, Wouter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833178/
https://www.ncbi.nlm.nih.gov/pubmed/35101979
http://dx.doi.org/10.1073/pnas.2113927119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833178/
https://www.ncbi.nlm.nih.gov/pubmed/35101979
http://dx.doi.org/10.1073/pnas.2113927119

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