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High-speed atomic force microscopy reveals a three-state elevator mechanism in the citrate transporter CitS
The secondary active transporter CitS shuttles citrate across the cytoplasmic membrane of gram-negative bacteria by coupling substrate translocation to the transport of two Na(+) ions. Static crystal structures suggest an elevator type of transport mechanism with two states: up and down. However, no...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833178/ https://www.ncbi.nlm.nih.gov/pubmed/35101979 http://dx.doi.org/10.1073/pnas.2113927119 |