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Poly-2-methyl-2-oxazoline–modified bioprosthetic heart valve leaflets have enhanced biocompatibility and resist structural degeneration

Bioprosthetic heart valves (BHV) fabricated from glutaraldehyde-fixed heterograft tissue, such as bovine pericardium (BP), are widely used for treating heart valve disease, a group of disorders that affects millions. Structural valve degeneration (SVD) of BHV due to both calcification and the accumu...

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Detalles Bibliográficos
Autores principales: Zakharchenko, Andrey, Xue, Yingfei, Keeney, Samuel, Rock, Christopher A., Alferiev, Ivan S., Stachelek, Stanley J., Takano, Hajime, Thomas, Tina, Nagaswami, Chandrasekaran, Krieger, Abba M., Chorny, Michael, Ferrari, Giovanni, Levy, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833185/
https://www.ncbi.nlm.nih.gov/pubmed/35131859
http://dx.doi.org/10.1073/pnas.2120694119