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Convergent clonal selection of donor- and recipient-derived CMV-specific T cells in hematopoietic stem cell transplant patients

Competition between antigen-specific T cells for peptide:MHC complexes shapes the ensuing T cell response. Mouse model studies provided compelling evidence that competition is a highly effective mechanism controlling the activation of naïve T cells. However, assessing the effect of T cell competitio...

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Detalles Bibliográficos
Autores principales: Erickson, Jami R., Stevens-Ayers, Terry, Mair, Florian, Edmison, Bradley, Boeckh, Michael, Bradley, Philip, Prlic, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833188/
https://www.ncbi.nlm.nih.gov/pubmed/35105810
http://dx.doi.org/10.1073/pnas.2117031119