Antiviral drug discovery by targeting the SARS-CoV-2 polyprotein processing by inhibition of the main protease

The spread of SARS-CoV-2, the causative agent for COVID-19, has led to a global and deadly pandemic. To date, few drugs have been approved for treating SARS-CoV-2 infections. In this study, a structure-based approach was adopted using the SARS-CoV-2 main protease (M(pro)) and a carefully selected da...

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Detalles Bibliográficos
Autores principales: Kandeel, Mahmoud, Kim, Jinsoo, Fayez, Mahmoud, Kitade, Yukio, Kwon, Hyung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833224/
https://www.ncbi.nlm.nih.gov/pubmed/35186496
http://dx.doi.org/10.7717/peerj.12929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833224/
https://www.ncbi.nlm.nih.gov/pubmed/35186496
http://dx.doi.org/10.7717/peerj.12929

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