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Targeting Oncogenic Pathways in the Era of Personalized Oncology: A Systemic Analysis Reveals Highly Mutated Signaling Pathways in Cancer Patients and Potential Therapeutic Targets

SIMPLE SUMMARY: Currently, genomic databases offer a vast amount of information on mutational profiles and records of statistically significant genetic associations with diseases. However, the functional interpretation of frequently mutated genes implicated in cancer is essential for the development...

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Detalles Bibliográficos
Autores principales: Karagiannakos, Alexandros, Adamaki, Maria, Tsintarakis, Antonis, Vojtesek, Borek, Fåhraeus, Robin, Zoumpourlis, Vassilis, Karakostis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833388/
https://www.ncbi.nlm.nih.gov/pubmed/35158934
http://dx.doi.org/10.3390/cancers14030664