Glioblastoma Cells Counteract PARP Inhibition through Pro-Survival Induction of Lipid Droplets Synthesis and Utilization

SIMPLE SUMMARY: Glioblastoma multiforme (GBM) is the most common and deadly primary brain tumor in adults and one of the most aggressive cancers. The use of Poly ADP-Ribose Polymerase (PARP) inhibitors is being expanded as therapeutic alternative in multiple types of cancer beyond BRCA1/2 mutant bre...

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Detalles Bibliográficos
Autores principales: Majuelos-Melguizo, Jara, Rodríguez-Vargas, José Manuel, Martínez-López, Nuria, Delgado-Bellido, Daniel, García-Díaz, Ángel, Yuste, Víctor J., García-Macía, Marina, López, Laura M., Singh, Rajat, Oliver, F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833394/
https://www.ncbi.nlm.nih.gov/pubmed/35158994
http://dx.doi.org/10.3390/cancers14030726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833394/
https://www.ncbi.nlm.nih.gov/pubmed/35158994
http://dx.doi.org/10.3390/cancers14030726

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