Successful Incorporation of Exosome-Capturing Antibody-siRNA Complexes into Multiple Myeloma Cells and Suppression of Targeted mRNA Transcripts

SIMPLE SUMMARY: Although nucleic acid medicines are expected to function as new therapeutic agents, their targeted delivery into cancer cells, particularly hematologic cancer cells, via systemic administration, is limited. Based on our previous finding that tumor cell-derived exosomes are preferenti...

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Detalles Bibliográficos
Autores principales: Soma, Emi, Yamayoshi, Asako, Toda, Yuki, Mishima, Yuji, Hosogi, Shigekuni, Ashihara, Eishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833399/
https://www.ncbi.nlm.nih.gov/pubmed/35158834
http://dx.doi.org/10.3390/cancers14030566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833399/
https://www.ncbi.nlm.nih.gov/pubmed/35158834
http://dx.doi.org/10.3390/cancers14030566

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