Measuring heritable contributions to Alzheimer’s disease: polygenic risk score analysis with twins

The heritability of Alzheimer’s disease estimated from twin studies is greater than the heritability derived from genome-based studies, for reasons that remain unclear. We apply both approaches to the same twin sample, considering both Alzheimer’s disease polygenic risk scores and heritability from...

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Detalles Bibliográficos
Autores principales: Karlsson, Ida K., Escott-Price, Valentina, Gatz, Margaret, Hardy, John, Pedersen, Nancy L., Shoai, Maryam, Reynolds, Chandra A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833403/
https://www.ncbi.nlm.nih.gov/pubmed/35169705
http://dx.doi.org/10.1093/braincomms/fcab308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833403/
https://www.ncbi.nlm.nih.gov/pubmed/35169705
http://dx.doi.org/10.1093/braincomms/fcab308

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