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Alternative NF-κB Signaling Discriminates Induction of the Tumor Marker Fascin by the Viral Oncoproteins Tax-1 and Tax-2 of Human T-Cell Leukemia Viruses

SIMPLE SUMMARY: The actin-bundling protein Fascin is upregulated in many types of cancers, including adult T-cell leukemia/lymphoma, a tumor induced by the oncogenic retrovirus human T-cell leukemia virus type 1 (HTLV-1). Transcriptional regulation of Fascin is heterogeneous between different cell t...

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Detalles Bibliográficos
Autores principales: Heym, Stefanie, Mohr, Caroline F., Engelbrecht, Hanna C., Fleckenstein, Bernhard, Thoma-Kress, Andrea K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833421/
https://www.ncbi.nlm.nih.gov/pubmed/35158803
http://dx.doi.org/10.3390/cancers14030537