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Intrinsic Cellular Susceptibility to Barrett’s Esophagus in Adults Born with Esophageal Atresia

SIMPLE SUMMARY: We investigated the increased prevalence of Barrett’s esophagus in adults with esophageal atresia. A higher polygenic risk score and disturbances in inflammatory, stress response and oncological pathways upon acid exposure suggest a genetic susceptibility and increased induction of i...

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Detalles Bibliográficos
Autores principales: ten Kate, Chantal A., de Klein, Annelies, de Graaf, Bianca M., Doukas, Michail, Koivusalo, Antti, Pakarinen, Mikko P., van der Helm, Robert, Brands, Tom, IJsselstijn, Hanneke, van Bever, Yolande, Wijnen, René M.H., Spaander, Manon C.W., Brosens, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833471/
https://www.ncbi.nlm.nih.gov/pubmed/35158780
http://dx.doi.org/10.3390/cancers14030513