Combined Inhibition of Polo-Like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells

SIMPLE SUMMARY: Systemic Mastocytosis (SM) is a rare disease resulting from a clonal proliferation of mast cells. Despite the rarity of the disease, its advanced forms remain a hard core to manage in clinical practice. At this time, there are few therapeutic options available, such as midostaurin an...

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Detalles Bibliográficos
Autores principales: Mancini, Manuela, Monaldi, Cecilia, De Santis, Sara, Rondoni, Michela, Papayannidis, Cristina, Sartor, Chiara, Curti, Antonio, Bruno, Samantha, Cavo, Michele, Soverini, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833529/
https://www.ncbi.nlm.nih.gov/pubmed/35159005
http://dx.doi.org/10.3390/cancers14030738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833529/
https://www.ncbi.nlm.nih.gov/pubmed/35159005
http://dx.doi.org/10.3390/cancers14030738

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