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Combined Inhibition of Polo-Like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells
SIMPLE SUMMARY: Systemic Mastocytosis (SM) is a rare disease resulting from a clonal proliferation of mast cells. Despite the rarity of the disease, its advanced forms remain a hard core to manage in clinical practice. At this time, there are few therapeutic options available, such as midostaurin an...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833529/ https://www.ncbi.nlm.nih.gov/pubmed/35159005 http://dx.doi.org/10.3390/cancers14030738 |