c-Myc Targets HDAC3 to Suppress NKG2DL Expression and Innate Immune Response in N-Type SCLC through Histone Deacetylation

SIMPLE SUMMARY: Natural killer group 2, member D ligand (NKG2DL) is the most relevant ligand of NK cells to perform immune surveillance and is rarely expressed in most small cell lung cancer (SCLC) with the unclear mechanism. This study aimed to investigate the mechanisms underlying the NKG2DL defic...

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Detalles Bibliográficos
Autores principales: Zhao, Peiyan, Sun, Xiaodan, Li, Hui, Liu, Yan, Cui, Yanan, Tian, Lin, Cheng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833590/
https://www.ncbi.nlm.nih.gov/pubmed/35158730
http://dx.doi.org/10.3390/cancers14030457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833590/
https://www.ncbi.nlm.nih.gov/pubmed/35158730
http://dx.doi.org/10.3390/cancers14030457

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