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High Metabolic Dependence on Oxidative Phosphorylation Drives Sensitivity to Metformin Treatment in MLL/AF9 Acute Myeloid Leukemia

SIMPLE SUMMARY: Acute myeloid leukemia is a group of metabolic heterogeneous cancers, of which the long-term overall survival is still poor, especially in elderly patients. Targeting metabolic reprogramming in leukemic cells is becoming a promising strategy. The aim of our research was to explore th...

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Detalles Bibliográficos
Autores principales: Liu, Longlong, Patnana, Pradeep Kumar, Xie, Xiaoqing, Frank, Daria, Nimmagadda, Subbaiah Chary, Rosemann, Annegret, Liebmann, Marie, Klotz, Luisa, Opalka, Bertram, Khandanpour, Cyrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833593/
https://www.ncbi.nlm.nih.gov/pubmed/35158754
http://dx.doi.org/10.3390/cancers14030486