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High Metabolic Dependence on Oxidative Phosphorylation Drives Sensitivity to Metformin Treatment in MLL/AF9 Acute Myeloid Leukemia
SIMPLE SUMMARY: Acute myeloid leukemia is a group of metabolic heterogeneous cancers, of which the long-term overall survival is still poor, especially in elderly patients. Targeting metabolic reprogramming in leukemic cells is becoming a promising strategy. The aim of our research was to explore th...
Autores principales: | Liu, Longlong, Patnana, Pradeep Kumar, Xie, Xiaoqing, Frank, Daria, Nimmagadda, Subbaiah Chary, Rosemann, Annegret, Liebmann, Marie, Klotz, Luisa, Opalka, Bertram, Khandanpour, Cyrus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833593/ https://www.ncbi.nlm.nih.gov/pubmed/35158754 http://dx.doi.org/10.3390/cancers14030486 |
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