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The Role of Thymine DNA Glycosylase in Transcription, Active DNA Demethylation, and Cancer

SIMPLE SUMMARY: Thymine DNA Glycosylase (TDG) is a DNA repair protein that plays an important role in gene regulation. Recent studies have shown that TDG interacts with various transcription factors to activate target genes. TDG also functions in a pathway known as active DNA demethylation, which re...

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Detalles Bibliográficos
Autores principales: Onabote, Oladapo, Hassan, Haider M., Isovic, Majdina, Torchia, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833622/
https://www.ncbi.nlm.nih.gov/pubmed/35159032
http://dx.doi.org/10.3390/cancers14030765