Novel Repositioning Therapy for Drug-Resistant Glioblastoma: In Vivo Validation Study of Clindamycin Treatment Targeting the mTOR Pathway and Combination Therapy with Temozolomide

SIMPLE SUMMARY: Given the significant costs and lengthy timelines of drug development and clinical trials, drug repositioning is a promising alternative to find effective treatments for brain tumors quickly and inexpensively. In the present study, using a simple drug screen of macrolides, we found t...

Descripción completa

Detalles Bibliográficos
Autores principales: Eda, Takeyoshi, Okada, Masayasu, Ogura, Ryosuke, Tsukamoto, Yoshihiro, Kanemaru, Yu, Watanabe, Jun, On, Jotaro, Aoki, Hiroshi, Oishi, Makoto, Takei, Nobuyuki, Fujii, Yukihiko, Natsumeda, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833675/
https://www.ncbi.nlm.nih.gov/pubmed/35159037
http://dx.doi.org/10.3390/cancers14030770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833675/
https://www.ncbi.nlm.nih.gov/pubmed/35159037
http://dx.doi.org/10.3390/cancers14030770

Ejemplares similares