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Cancer-Associated Fibroblasts and Tumor Cells in Pancreatic Cancer Microenvironment and Metastasis: Paracrine Regulators, Reciprocation and Exosomes

SIMPLE SUMMARY: Cancer-associated fibroblasts in the stromal tumor microenvironment play a key role in cancer progression, invasion, metastasis, and therapy resistance. Cancer-associated fibroblasts communicate with tumor cells through diverse factors, such as growth factors, hedgehog proteins, cyto...

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Detalles Bibliográficos
Autores principales: Sunami, Yoshiaki, Häußler, Johanna, Zourelidis, Anais, Kleeff, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833704/
https://www.ncbi.nlm.nih.gov/pubmed/35159011
http://dx.doi.org/10.3390/cancers14030744